MHC Monomers and Tetramers - easYmer® MHC class I and class MHC II

MHC class I affinity predictors

NetMHC

NetMHCpan

MHC class I stability predictors

NetMHCstab

NetMHCstabpan

MHC class II affinity predictors

NetMHCII

NetMHCIIpan

Four new easYmers®
We are now adding HLA-A*02:06, HLA-B*38:01, HLA-B*44:03 and HLA-B*51:01 to our portfolio of loadable HLA molecules | easYmers® The peptide loadable MHC class I easYmer® portfolio represents, by far, the highest coverage of HLA allotypes across the regions of the world and ethnic groups. Exploitation of cellular immunity is important for future immunotherapies and general vaccine strategies (e.g covid-19) and...

Bonte, P.E., et al., Single-cell RNA-seq-based proteogenomics identifies glioblastoma-specific transposable elements encoding HLA-I-presented peptides. Cell Rep, 2022. 39(10): p. 110916.
Oberhardt, V., et al., Rapid and stable mobilization of CD8(+) T cells by SARS-CoV-2 mRNA vaccine. Nature, 2021.
Sahin, U., et al., BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans. Nature, 2021.
Bigot, J., et al., Splicing patterns in SF3B1 mutated uveal melanoma generate shared immunogenic tumor-specific neo-epitopes. Cancer Discov, 2021.
Schulien, I., et al., Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells. Nature Medicine, 2021. 27(1): p. 78-85.

HLA Monomer Tetramer